Dr. Al-Samkari is Associate Director of the Massachusetts General Hospital HHT Center of Excellence. He is a hematologist who specializes in bleeding and clotting disorders, with a specific focus in bleeding disorders and HHT. In addition to management of bleeding, he specializes in management of anemia associated with HHT, typically due to severe and often refractory iron deficiency. He has seen and treated over a hundred patients with HHT with bleeding and/or anemia. He is a recognized leader in investigation and clinical treatment of the treatment of HHT with anti-angiogenic therapies, including bevacizumab (Avastin).